Lose Weight
Explore research peptides commonly discussed for appetite regulation, fat metabolism, and body-composition support—then compare providers and expected trajectories.
10
Peptides
45
Research Studies
- ●Reduces Appetite
- ●Increases Fat Burning
- ●Improves Metabolism
- ●Preserves Lean Muscle
Top Peptides for Lose Weight
- #1 Best OverallRetatrutide
Retatrutide
Avg. Weight Loss
24%
- Research Quality
- High
- Side Effects
- Mild GI
- Cost
- $$$
- Best For
- Max fat loss
- #2 Best for Most PeopleTirzepatide
Tirzepatide
Avg. Weight Loss
21%
- Research Quality
- High
- Side Effects
- Mild GI
- Cost
- $$
- Best For
- Balanced results
- #3 Best for BeginnersCagrilintide
Cagrilintide
Avg. Weight Loss
—
- Research Quality
- Strong
- Side Effects
- Mild GI
- Cost
- $$
- Best For
- Appetite research
Research Backed
View all studies- ◆
Phase 3 SURMOUNT-5 Trial Results
Dual-agonist outcomes for body weight vs comparator therapy over 72 weeks.
NEJM, 2024
- ◆
Retatrutide Phase 2 Dose Response
Triple-agonist weight-loss signals across escalating dose cohorts.
Lancet, 2023
- ◆
GLP-1 Lean Mass Preservation Review
Narrative review of lean-mass outcomes alongside fat-mass reduction.
Obesity Reviews, 2024
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