CJC-1295
A GHRH analogue commonly discussed in growth-hormone-axis and recovery-oriented research contexts. See CJC-1295 DAC for the long-acting molecule used in published human dosing studies.
- Muscle
- Recovery
- Secretagogue
GLP-1
Slows gastric emptying and reduces appetite signals.
GIP
Supports insulin response and metabolic efficiency.
Glucagon
Increases energy expenditure and fat oxidation.
What is CJC-1295?
Retatrutide is an investigational triple agonist that simultaneously targets GLP-1, GIP, and glucagon receptors. It has been studied as a once-weekly subcutaneous injection in Phase 2 and Phase 3 trials, with doses ranging from 1 mg to 12 mg.
Type
Peptide
Starting Dose
2 mg weekly
Max Studied
12 mg weekly
Development
Phase 3 Trials
How It Works
CJC-1295 is an investigational research compound reviewed for educational comparison.
GLP-1 Agonist
- ✓Reduces hunger cues
- ✓Slows gastric emptying
- ✓Improves glycemic control
GIP Agonist
- ✓Enhances insulin response
- ✓Supports nutrient partitioning
- ✓Complements GLP-1 effects
Glucagon Agonist
- ✓Raises energy expenditure
- ✓Increases fat oxidation
- ✓Supports metabolic rate
Result
Reduced Calorie Intake
Increased Fat Burning
Significant Weight Loss
How CJC-1295 Compares
| Feature | Retatrutide | Tirzepatide | Semaglutide |
|---|---|---|---|
| Receptor Activity | GIP + GLP-1 + glucagon | GIP + GLP-1 | GLP-1 |
| Typical Frequency | Weekly | Weekly | Weekly |
| Regulatory Status | Investigational | FDA approved (certain indications) | FDA approved (certain indications) |
| Phase 2 avg. loss (top dose) | 24.2% @ 48 wks | — | — |
Side Effects
Commonly discussed effects in research summaries include mild gastrointestinal symptoms (nausea, reduced appetite). Always follow a qualified clinician's protocol. This page is educational only.
Dosage
Research protocols often use once-weekly subcutaneous administration with gradual titration. Use the Dosage Calculator to explore reconstitution math for your vial size.
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